ACoP8 Preliminary Program

SATURDAY October 14th

7:00 AM

8:00 AM

Breakfast and Registration for Pre-meeting Workshops

 

8:00 AM

5:00 PM

Pre-Meeting Workshops (separate registration required)

 

     Physiological modelling of therapeutic proteins and antibody-drug conjugates: Simcyp/Certara  
   

Systems Pharmacology and PBPK modeling using PK-Sim and MoBi. A step by step lesson how to build and apply PBPK models - An Open Systems Pharmacology Workshop  (Bayer)

 
   

New and Advanced Features of NONMEM 7.4 (ICON)

 

SUNDAY October 15th

7:00 AM 

8:00 AM

Breakfast and Registration for Pre-meeting Workshops 

 

7:00 AM

8:00 AM

Breakfast and Registration for ACoP7 Pre-conference

 

8:00 AM

5:00 PM

Pre-Meeting Workshops

 

   

Bridging PBPK with POPPK for Pediatrics:  (Simcyp/Certara)

 
   

Parameter Estimation and Pharmacodynamics (PE/PD) (Simcyp/Certara)

 
   

Advanced Use of Stan, rstan and Torsten for Pharmacometric Applications (Metrum)

 
   

Modeling Delays in Pharmacokinetics and Pharmacodynamics (U of Buffalo)

 

8:15 AM

5:00 PM

ACoP8 Pre-conference

“Systems Pharmacology: From Innovation to Impact

 

12:00 PM

5:30 PM

Registration for ACoP8

 

5:30 PM

7:00 PM

Opening Session

 

 

 

(5:30 - 6:30)

Conference Opening - Conference Highlights

ISoP Awards Presentation:

ISoP Leadership Award

ISoP Innovation Award

ISoP Fellow Inductees

 

 

   

Sheiner Award Lecture:

 

7:30 PM

11:00 PM

ACoP8 Opening Reception

 

MONDAY October 16th

7:30 AM

9:30 AM

Breakfast/Registration/Contributed Poster Session 1/Exhibits

 

9:30 AM

9:45 AM

President Address - ISoP 2017. The Year in Review

President-Elect Address - ISoP:  Looking Forward

 

9:45 AM

11:30 AM

Session 1: Quantification of Co-variate Effects for Labeling

 

 

 

   

Session 1b: Systems, Empirical or In-between: Bridging the Gap between Mechanism and Statistics

 

11:30 AM

1:00 PM

Student/Trainee Mentoring Session with Lunch 

[free, separate registration required]

 

11:30 AM

1:00 PM

Lunch/Posters/Exhibits

 
   

Lunch and Learn - The application of pharmacometrics to the development of reversal agents for Direct Oral Anticoagulants

 

1:00 PM

2:00 PM

State-of-the-Art Lecture

 

2:00 PM

2:15 PM

Break

 

2:15 PM

3:45 PM

Session 2a: Model-Based Drug Development of Therapeutic Proteins in Autoimmune Diseases

 

 

 

 

Session 2b: Healthcare Analytics and Pharmacometrics - Bench to Bedside Progression- Opportunities for Synergy

 

 

 

Session 2c: Advancing the Use of Quantitative Systems Pharmacology in Drug Development and Regulatory Decisions

 

3:45 PM

4:00 PM

Break

 

4:00 PM

5:30 PM

Session 3a: Effective application of modelling, simulation and knowledge sharing across quantitative disciplines

 

    Session 3b: Mechanistic joint models for longitudinal and time-to-event data: recent advances and specific applications in oncology drug development

 

    Session 3c: Bridging Toxicity and Efficacy: How QSP Models Can Incorporate Both Safety and Efficacy Endpoints for More Efficient Drug Development

 

5:30 PM

6:30 PM

Alumni Receptions

[by invitation only]

 

6:15 PM

11:00 PM

Social Event

 

TUESDAY October 17th

7:30 AM

9:00 AM

Breakfast/Registration/Contributed Poster Session 2/Exhibits

 

9:00 AM

10:30 AM

Podium Presentation of ACoP7 Quality Awards and Trainee Awards

 

 

10:45 AM

12:15 PM

Session 4a: Marriage between quantitative approaches and regulatory science: a reality check on where we are

 

   

Session 4b: Adherence to Medications: A Crucial Missing Link in Quantitative Clinical Pharmacology

 

   

Session 4c: Mathematical Pharmacology: a distinct discipline of pharmacometrics

 

12:15 PM

1:30 PM

Lunch/Posters/Exhibits

 

12:15 PM

1:30 PM

Meet and Greet The SIGs luncheon

 

12:15 PM

1:30 PM

JPKPD Editorial Board Meeting (by invitation only)

 

1:30 PM

2:30 PM

Keynote Lecture

 

 

2:30 AM

2:45 AM

Break

 

2:45 AM

 4:30 PM

Session 5a: Model informed Drug Discovery and Development (MID3): industry good practice, regulatory expectations, and technical gaps

 

   

Session 5b: Optimal design: just nerdy or useful?

 

   

Session 5c:  System Pharmacology Approach to Facilitate Design of Combination Therapy for Effective Cancer Immunotherapy


 

4:30 PM

4:45 PM

Break

 

4:45 PM

6:30 PM

Innovative Communications

 

6:30 PM

7:30 PM

 

Presidential Reception

 

[by invitation only]

 

 

WEDNESDAY October 18th

7:00 AM

9:00 AM

Breakfast/Contributed Poster Session 3/Exhibits

 

9:00 AM

10:30 AM

Session 6a: Source Data Quality for Pharmacometric programming: Challenges and possible solutions 

 

   

Session 6b: Model-Aided Drug Development for Respiratory Diseases: Approaches & Applications

 

 

   

Session 6c: Data Needs and Model Qualification for Drug Safety Applications of QSP

 

10:30 AM 10:45 PM

Break

 

10:45 PM

12:15 PM

Session 7a: Model-Aided Drug Development of Cancer Immunotherapeutics: Approaches & Applications

 

   

Session 7b: Neighbor’s Envy Owner’s Pride - Comparator Analysis for Drug Development and Market Access

 
   

Session 7c: Industrial-Strength Infrastructure for Pharmacometrics

 

12:15 PM

12:30 PM

Closing Remarks

 

1:00 PM

2:00 PM

Student/Trainee Event with Lunch: 

[free, separate registration required]

 

 

 

Lunch & Meet ISoP Board and Posters

 

2:00 PM

4:30 PM

ACoP9 meets ACoP8

[by invitation only]
 

 2:00 PM

 5:30 PM

ACoP8 Tutorials 

[free, separate registration required]

 

   

Tutorial 1: Building Shiny Apps for Pharmacometrics

 

   

Tutorial 2: Modular QSP design - Approaches to speed up the QSP model development 

 

   

Tutorial 3: Pharmacometrics + Applied Math = Better QSP 

 

   

Tutorial 4: Student Tutorial:

 

THURSDAY October 19th

7:00 AM

8:00 AM

Breakfast and Registration for Post-meeting Workshops

 

8:00 AM

5:00 PM

Post-meeting workshops

 

   

R as a single-step platform for PK/PD and PBPK/QSP M&S: integration of model estimation, optimization, simulation, and reporting. (Metrum)